Sakata R, Niwa K, Ugarte La Torre D, Gu C, Tahara E, Takada S, Nishiyama T, Opening of cohesin's SMC ring is essential for timely DNA replication and DNA loop formation. Cell Rep. 35(4):108999 (2021)
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Nishiyama T, Compartments in the Ring. Molecular Cell 75(2), 201-203 (2019).
Nishiyama T, Cohesion and cohesin-dependent chromatin organization. Curr Opin Cell Biol. 58, 8-14 (2018).
Nishiyama T, Single-molecule analyses of cohesin and condensin. Experimental Medicine (special issue) Vol.36 No.17 126-134 (2018).
Yamada T, Tahara E, Kanke M, Kuwata K, Nishiyama T. Drosophila Dalmatian combines sororin and shugoshin roles in establishment and protection of cohesion. The EMBO Journal 36, 1513-1527 (2017).
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Kanke M, Tahara E, Huis in't Veld PJ, Nishiyama T. Cohesin acetylation and Wapl‐Pds5 oppositely regulate translocation of cohesin along DNA. The EMBO Journal 35, 2686-2698 (2016).
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→プレスリリース
Nishiyama T, Sykora MM, Huis In 't Veld PJ, Mechtler K, Peters JM. Aurora B and Cdk1 mediate Wapl activation and release of acetylated cohesin from chromosomes by phosphorylating Sororin. Proc Natl Acad Sci U S A. 110, 13404-9 (2013).
Tedeschi A, Wutz G, Huet S, Jaritz M, Wuensche A, Schirghuber E, Davidson IF, Tang W, Cisneros DA, Bhaskara V, Nishiyama T, Vaziri A, Wutz A, Ellenberg J and Peters JM. Wapl is an essential regulator of chromatin structure and chromosome segregation
Nature 501, 564-8 (2013).
Peters JM. Nishiyama T. Sister Chromatid Cohesion. “DNA replication” (eds Stephen D. Bell, Marcel Méchali, and Melvin L. DePamphilis), Cold Spring Harb Perspect Biol. 2012 Nov 1;4(11).
Nishiyama T, Ladurner R, Schmitz J, Kreidl E, Schleiffer A, Bhaskara V, Bando M, Shirahige K, Hyman AA, Mechtler K, Peters JM. Sororin mediates sister chromatid cohesion by antagonizing Wapl. Cell 143, 737-49 (2010).
Nishiyama T, Ohsumi K. Molecular mechanisms for meiotic arrest that is cancelled by fertilization in vertebrate eggs. Protein, Nucleic Acid and Enzyme (3(3), 207-16 (2008).
Nishiyama T, Yoshizaki N, Kishimoto T, Ohsumi K. Transient activation of calcineurin is essential to initiate embryonic development in Xenopus laevis. Nature. 449, 341-345 (2007).
Nishiyama T, Ohsumi K, Kishimoto T. Phosphorylation of Erp1 by p90rsk is required for cytostatic factor arrest in Xenopus laevis eggs. Nature. 446, 1096-1099 (2007).
