Publication list 

Original articles

126. Machida, Y., Suzuki, T., Sasabe, M., Iwakawa, H., Kojima, S., and Machida, C. (2022). Arabidopsis ASYMMETRIC LEAVES2 (AS2): roles in plant morphogenesis,cell division, and pathogenesis. Journal of Plant Research 133:3-14
https://doi.org/10.1007/s10265-021-01349-6

125. Maeda, K., Sasabe, M., Hanamata, S., Machida, Y., Hasezawa, S. and Higaki, T. (2020). Actin Filament Disruption Alters Phragmoplast Microtubule Dynamics during the Initial Phase of Plant Cytokinesis. Plant Cell Physiol. 61(3):445-456. Mar 1.
https://doi.org/10.1093/pcp/pcaa003

124. Luo, L., Ando, S., Sakamoto, Y., Suzuki, T., Takahashi, H., Ishibashi, N., Kojima, S., Kurihara, D., Higashiyama, T., Yamamoto, K.-T., Matsunaga, S., Machida, C., Sasabe, M. and Machida, Y. (2020). The formation of perinucleolar bodies is important for normal leaf development and requires the zinc-finger DNA-binding motif in Arabidopsis ASYMMETRIC LEAVES2. Plant J. 101, 1118-1134. Mar [First pub 2019 Oct 22].
https://doi.org/10.1111/tpj.14579  cover

123. Vial-Pradel, S., Hasegawa, Y., Nakagawa, A., Miyaki, S., Machida, Y., Kojima, S., Machida, C. and Takahashi, H. (2019). SIMON: Simple methods for analyzing DNA methylation by targeted bisulfite next-generation sequencing. Plant Biotechnol (Tokyo). 36(4):213-222. Dec 25.
https://doi.org/10.5511/plantbiotechnology.19.0822a

122. Luong.T-Q., Keta, S., Asai, T., Kojima, S., Nakagawa. A., Micol, J.-L., Xia, S., Machida, Y. and Machida, C. (2018). A genetic link between epigenetic repressor AS1-AS2 and DNA replication factors in establishment of adaxial-abaxial leaf polarity of Arabidopsis. Plant Biotechnology 35, 39–49.
https://doi.org/10.5511/plantbiotechnology.18.0129b

121. Vial-Pradel. S., Keta, S., Nomoto. M., Luo, L., Takahashi, H., Suzuki, M., Yokoyama, Y., Sasabe. M., Kojima. S., Tada. Y.,Machida. Y. and Machida, C. (2018). Arabidopsis zinc-finger-like protein ASYMMETRIC LEAVES2 (AS2) and two nucleolar proteins maintain gene body DNA methylation in the leaf polarity gene ETTIN (ARF3). Plant & Cell Physiology 59 (7), 1385–1397. 
https://doi.org/10.1093/pcp/pcy031

120. Ohbayashi, I., Lin, C.-Y., Shinohara, N., Matsumura, Y., Machida, Y., Horiguchi, G., Tsukaya, H.and Sugiyama, M. (2017). Evidence for a Role of ANAC082 as a Ribosomal Stress Response Mediator Leading to Growth Defects and Developmental Alterations in Arabidopsis. The Plant Cell Vol. 29: 2644–2660, October 2017
https://doi.org/10.1105/tpc.17.00255

119. Li, H., Sun, B., Sasabe, M., Deng, X.-G., Machida, Y., Lin, H., Lee Y.-R. and Liu, B. (2017). Arabidopsis MAP65-4 Plays A Role in Phragmoplast Microtubule Organization and Marks the Cortical Cell Division Site. New Phytologist 215: 187–201. 
https://doi.org/10.1111/nph.14532

118. Suzuki, T., Matsushima, C., Nishimura, S., Higashiyama, T., Sasabe, M. Machida, Y. (2016). Identification of Phosphoinositide-binding Protein PATELLIN2 as a Substrate of Arabidopsis MPK4 MAP Kinase during Septum Formation in Cytokinesis. Plant Cell Physiol. Aug;57(8):1744-55. Epub 2016 May 19.
https://doi.org/10.1093/pcp/pcw098

117. Matsumura, Y., Ohbayashi, I., Takahash, H., Kojima, S., Ishibashi, N., Keta, S, Nakagawa, A., Hayashi, R., Saéz-Vásquez, J., Echeverria, M., Sugiyama, M., Nakamura,K., Machida, C. and Machida, Y. (2016). A genetic link between epigenetic repressor AS1-AS2 and a putative small subunit processome in leaf polarity establishment of Arabidopsis. Biology Open 5(7): 942-954.
https://doi.org/10.1242/bio.019109

116. Kawamoto, N., Sasabe, M., Endo, M., Machida, Y. and Araki, T. (2015). Calcium-dependent protein kinases responsible for the phosphorylation of a bZIP transcription factor FD crucial for the florigen complex formation. Sci Rep. 2015 Feb 9; 5: 834.
https://doi.org/10.1038/srep08341

115. Saito, T., Fujikawa, H., Haga, N., Suzuki, T., Machida, Y. and Ito, M. (2015). Genetic interaction between G2/M phase-specific transcription factor MYB3R4 and MAPKKK ANP3 for execution of cytokinesis in Arabidopsis thaliana. Plant Signal. Behav. 2015 ; 10(3) : e990817.
https://doi.org/10.4161/15592324.2014.990817

114. Sasabe, M., Ishibashi, N., Haruta, T., Minami, A., Kurihara, D., Higashiyama, T., Nishihama, R., Ito, M. and Machida, Y. (2015). The carboxyl-terminal tail of the stalk of Arabidopsis NACK1/HINKEL kinesin is required for its localization to the cell plate formation site. J. Plant Res. 128:327–336.
https://doi.org/10.1007/s10265-014-0687-2

113. Araki, S., Kato, K., Suzuki, T., Okumura, T., Machida, Y. and Ito, M. (2013). Cosuppression of NtmybA1 and NtmybA2 causes downregulation of G2/M phase-expressed genes and negatively affects both cell division and expansion in tobacco. Plant Signal. Behav. Oct; 8(10)
https://doi.org/10.4161/psb.26780

112. Ishibashi, N., Machida, C. and Machida, Y. (2013). ASYMMETRIC LEAVES2 and FASCIATA2 cooperatively regulate the formation of leaf adaxial-abaxial polarity in Arabidopsis thaliana. Plant Biotechnology 30, 411-415.
https://doi.org/10.5511/plantbiotechnology.13.0513a

111. Murata, T., Sano, T., Sasabe, M., Nonaka, S., Higashiyama, T., Hasezawa, S., Machida, Y. and Hasebe, M. (2013). Mechanism of microtubule array expansion in the cytokinetic phragmoplast. Nat Commun Jun 17; 4:1967.  
https://doi.org/10.1038/ncomms2967

110. Iwasaki, M., Takahashi, H., Iwakawa, H., Nakagawa, A., Ishikawa, T., Tanaka, H., Matsumura, Y., Pekker, I., Eshed, Y., Vial-Pradel, S., Ito, T., Watanabe, Y., Ueno, Y., Fukazawa, H., Kojima, S., Machida, Y. and Machida, C. (2013). Dual regulation of ETTIN (ARF3) gene expression by AS1-AS2, which maintains the DNA methylation level, is involved in stabilization of leaf adaxial-abaxial partitioning in Arabidopsis. Development 140,1958-1969.
https://doi.org/10.1242/dev.085365

109. Takahashi, H., Iwakawa, H., Ishibashi, N., Kojima, S., Matsumura, Y., Prananingrum, P., Iwasaki, M., Takahashi, A., Ikezaki, M., Luo, L., Kobayash, T., Machida, Y. and Machida, C. (2013). Meta-analyses of microarrays of Arabidopsis asymmetric leaves1 (as1), as2 and their modifying mutants reveal a critical role of the ETT pathway in stabilization of adaxial-abaxial patterning and cell division during leaf development. Plant Cell Physiol.54 (3), 418-431.
https://doi.org/10.1093/pcp/pct027

108. Araki, S., Machida, Y. and Ito, M. (2012). Virus-induced silencing of NtmybA1 and NtmybA2causes incomplete cytokinesis and reduced shoot elongation in Nicotiana benthamiana. Plant Biotechnology 29, 483-487.  
https://doi.org/10.5511/plantbiotechnology.12.1004a

107. Kinoshita, N., Wang, H., Kasahara, H., Liu, J., MacPherson, C., Machida, Y., Kamiya, Y., Hannah, M.-A. and Chua, N.-H. (2012). IAA-Ala Resistant3, an Evolutionarily Conserved Target of miR167, Mediates Arabidopsis Root Architecture Changes during High Osmotic Stress. The Plant Cell, Vol. 24: 3590–3602.
https://doi.org/10.1105/tpc.112.097006

106. Takahashi, H., Nakagawa, A., Kojima, S., Takahashi, A., Cha, B.-Y., Woo, J.-T., Nagai, K., Machida, Y. and Machida, C. (2012). Discovery of novel rules for G-quadruplex-forming sequences in plants by using bioinformatics methods. J. Biosci. Bioeng. 2012 Nov;114(5):570-5.
https://doi.org/10.1016/j.jbiosc.2012.05.017

105. Nakagawa, A., Takahashi, H., Kojima, S., Sato, N., Ohga, K., Cha, B. Y., Woo, J.-T., Nagai, K., Horiguchi, G., Tsukaya, H., Machida, Y. and Machida, C. (2012). Berberine enhances defects in the establishment of leaf polarity in asymmetric leaves1 and asymmetric leaves2 of Arabidopsis thaliana. Plant Mol. Biol. 79(6), 569-581.
https://doi.org/10.1007/s11103-012-9929-7

104. Sugita, C., Kato, Y., Yoshioka, Y., Tsurumi, N., Iida, Y., Machida, Y. and Sugita, M. (2012). CRUMPLED LEAF (CRL) Homologs of Physcomitrella patens are Involved in the Complete Separation of Dividing Plastids. Plant Cell Physiol. 53(6), 1124-1133. Apr 17.
https://doi.org/10.1093/pcp/pcs058

103. Luo, L., Ando, S., Sasabe, M., Machida, C., Kurihara, D., Higashiyama, T. and Machida, Y. (2012). Arabidopsis ASYMMETRIC LEAVES2 protein required for leaf morphogenesis consistently forms speckles during mitosis of tobacco BY-2 cells via signals in its specific sequence. J. Plant Res. 125, 661-668.
https://doi.org/10.1007/s10265-012-0479-5

102. Ishibashi, N., Kanamaru, K., Ueno, Y., Kojima, S., Kobayashi, T., Machida, C. and Machida, Y. (2012). ASYMMETRIC-LEAVES2 and an ortholog of eukaryotic NudC domain proteins repress expression of AUXIN-RESPONSE-FACTOR and class 1 KNOX homeobox genes for development of flat symmetric leaves in Arabidopsis. Biology Open 1(3), 197-207.
https://doi.org/10.1242/bio.2012406

101. Keta, S., Iwakawa, H., Ikezaki, M., Semiarti, E., Kojima, S., Machida, Y. and Machida, C (2012). Roles of the ASYMMETRIC LEAVES2 gene in floral organ development in Arabidopsis thaliana. Plant Biotechnology 29, 1-8.
https://doi.org/10.5511/plantbiotechnology.11.1101a

100. Sasabe, M., Boudolf, V., De Veylder, L., Inzé, D., Genschik, P. and Machida, Y. (2011). Phosphorylation of a mitotic kinesin-like protein and a MAPKKK by cyclin-dependent kinases (CDKs) is involved in the transition to cytokinesis in plants. Proc. Natl. Acad. Sci. USA 108 (43), 17844-17849.
https://doi.org/10.1073/pnas.1110174108

99. Kojima, S., Iwasaki, M., Takahashi, H., Imai, T., Matsumura, Y., Fleury, D., Van Lijsebettens, M., Machida, Y. and Machida, C. (2011). ASYMMETRIC LEAVES2 and histone acetyl transferase complex Elongator are involved in the establishment of polarity in leaves of Arabidopsis thaliana. Plant Cell Physiol. 52, 1259-1273.
https://doi.org/10.1093/pcp/pcr083

98. Sasabe, M., Kosetsu, K., Hidaka, M., Murase, A. and Machida, Y. (2011). Arabidopsis thaliana MAP65-1 and MAP65-2 function redundantly with MAP65-3/PLEIADE in cytokinesis downstream of MPK4. Plant Signaling & Behavior 65, 743-747.
https://doi.org/10.4161/psb.6.5.15146

97. Kosetsu, K., Matsunaga, S., Nakagam, H., Colcombet, J., Sasabe, M., Soyano, T., Takahashi, T., Hirt, H. and Machida, Y. (2010). The MAP kinase MPK4 is required for cytokinesis in Arabidopsis thaliana. The Plant Cell 22, 3778-3790.
https://doi.org/10.1105/tpc.110.077164

96. Takahashi, Y., Soyano, T., Kosetsu, K., Sasabe, M. and Machida, Y. (2010). HINKEL kinesin, ANP MAPKKKs and MKK6/ANQ MAPKK, which phosphorylates and activates MPK4 MAPK, constitute a pathway that is required for cytokinesis in Arabidopsis thaliana. Plant Cell Physiol. 51, 1766-1776. Cover.
https://doi.org/10.1093/pcp/pcq135

95. Semiarti, E., Indrianto, A., Purwantoro, A., Martiwi, I.-N.-A., Feroniasanti, Y.- M.- L., Nadifah, F., Mercuriana, I.- S., Dwiyani, R., Iwakawa, H., Yoshioka, Y., Machida, Y. and Machida, C. (2010). High-frequency genetic transformation of Phalaenopsis amabilis orchid using tomato extract-enriched medium for the pre-culture of protocorms. J. Horticultural Science & Biotechnology 85 (3) 205–210.
https://doi.org/10.1080/14620316.2010.11512655

94. Tabata, R., Ikezaki, M., Fujibe, T., Aida, M., Tian, C.-E., Ueno, Y., Yamamoto, K.-T., Machida, Y., Nakamura, K. and Ishiguro, S. (2010). Arabidopsis AUXIN RESPONSE FACTOR6 and 8 Regulate Jasmonic Acid Biosynthesis and Floral Organ Development via Repression of Class 1 KNOX Genes. Plant Cell Physiol. .51, 164-175.
https://doi.org/10.1093/pcp/pcp176

93. Ikezaki, M., Kojima, M., Sakakibara, H., Kojima, S., Ueno, Y., Machida, C. and Machida, Y. (2009). Genetic networks regulated by ASYMMETRIC LEAVES1 (AS1) and AS2 in leaf development in Arabidopsis: KNOX genes control five morphological events. Plant J. 61(1), 70-82.
https://doi.org/10.1111/j.1365-313X.2009.04033.x

92. Chen, Y., Asano, T., Fujiwara, M.-T., Yoshida, S., Machida, Y. and Yoshioka, Y. (2009). Plant cells without detectable plastids are generated in the crumpled leaf mutant of Arabidopsis thaliana. Plant Cell Physiol. 50, 956-969.
https://doi.org/10.1093/pcp/pcp047

91. Krupnova, T., Sasabe, M., Ghebreghiorghis, L., Gruber, C. W., Hamada, T., Dehmel, V., Strompen, G., Stierhof, Y.-D. Lukowitz, W., Kemmerling, B., Machida, Y., Hashimoto, T., Mayer, U. and Juergens, G. (2009). Microtubule-associated kinase-like protein RUNKEL needed for cell plate expansion in Arabidopsis cytokinesis. Curr. Biol. 19, 518-523.
https://doi.org/10.1016/j.cub.2009.02.021

90. Matsumura, Y., Iwakawa, H., Machida, Y. and Machida, C. (2009). Characterization of genes in the ASYMMETRIC LEAVES2/LATERAL ORGAN BOUNDARIES (AS2/LOB) family in Arabidopsis thaliana and functional and molecular comparisons between AS2 and other family members. Plant J. 58, 525-537.
https://doi.org/10.1111/j.1365-313X.2009.03797.x

89. Fujita, H., Syono, K., Machida, Y. and Kawaguchi, K. (2008). Morphological effects of sinefungin, an inhibitor of S-adenosylmethionine-dependent methyltransferases, on Anabaena sp. PCC 7120. Microbes Environ. 23: 346-349.
https://doi.org/10.1264/jsme2.me08519

88. Soyano, T., Thitamadee, S., Machida, Y. and Chua, N.-H. (2008). DOMAIN genes, ASL19/LBD30 and ASL20/LBD18, control tracheary element differentiation in Arabidopsis. Plant Cell 20, 3359-3373.
https://doi.org/10.1105/tpc.108.061796

87. Takahashi, H., Iwakawa, H., Nakao, S., Ojio, T., Morishita, R., Morikawa, S., Machida, Y., Machida, C. and Kobayashi, T. (2008). Knowledge-based fuzzy adaptive resonance theory and the application to gene expression aanalysis of plants. J. Biosci. Bioeng. 106(6), 587-593.
https://doi.org/10.1263/jbb.106.587

86. Yang, J.-Y., Iwasaki, M., Machida, C., Machida, Y., Zhou, X. and Chua, N.-H. (2008). βC1, the pathogenicity factor of TYLCCNV, interacts with AS1 to alter leaf development and suppress selective jasmonic acid responses. Genes Dev. 22, 2564-2577.
https://doi.org/10.1101/gad.1682208

85. Kitakura, S., Terakura, S., Yoshioka, Y., Machida, C. and Machida, Y. (2008). Interaction between Agrobacterium oncoprotein 6b and a tobacco nucleolar protein that is homologous to TNP1 encoded by an Antirrhinum transposable element. J. Plant Research Jul;121(4):425-33.
https://doi.org/10.1007/s10265-008-0160-1

84. Ishikawa, T., Machida, C., Yoshioka, Y., Ueda, T., Nakano, A. and Machida, Y. (2008). The EMBRYO YELLOW gene, encoding a subunit of the conserved oligomeric Golgi complex, is required for appropriate cell expansion and meristem organization in Arabidopsis thaliana. Genes to Cells 13(6), 521-535.
https://doi.org/10.1111/j.1365-2443.2008.01186.x

83. Terakura, S., Ueno, Y., Tagami, H., Kitakura, S., Machida, C., Wabiko, H., Aiba, H., Otten, L., Tsukagoshi, H., Nakamura, K. and Machida, Y. (2007). An Oncoprotein from the plant pathogen Agrobacterium has histone-chaperone-like activity. Plant Cell 19, 2855-2865.
https://doi.org/10.1105/tpc.106.049551

82. Iwakawa, H., Iwasaki, M., Kojima, S., Ueno, Y., Soma, T., Tanaka, H., Semiarti, E., Machida, Y. and Machida, C. (2007). Expression of the ASYMMETRIC LEAVES2 gene in the adaxial domain of Arabidopsis leaves represses cell proliferation in this domain and is critical for the development of properly expanded leaves. Plant J. 51, 173-184.
https://doi.org/10.1111/j.1365-313X.2007.03132.x

81. Tanaka, H., Watanabe, M., Sasabe, M., Hiroe, T., Tanaka, T., Tsukaya, T., Ikezaki, M., Machida, C. and Machida, Y. (2007). Novel receptor-like kinase ALE2 controls shoot development by specifying epidermis in Arabidopsis. Development 134, 1643-1652.
https://doi.org/10.1242/dev.003533

80. Semiarti, E., Indrianto, A., Purwantoro, A., Isminingsih, S., Suseno, N., Ishikawa, T., Yoshioka, Y., Machida, Y. and Machida, C. (2007). Agrobacterium-mediated transformation of the wild orchid species Phalaenopsis amabilis. Plant Biotech. 24 (3)265-272.
https://doi.org/10.5511/plantbiotechnology.24.265

79. Ueno, Y., Ishikawa, T., Watanabe, K., Terakura, S., Iwakawa, H., Okada, K., Machida, C. and Machida, Y. (2007). Histone deacetylases and ASYMMETRIC LEAVES2 are involved in the establishment of polarity in leaves of Arabidopsis. Plant Cell 19(2), 445-457.
https://doi.org/10.1105/tpc.106.042325

78. Terakura, S., Kitakura, S., Ishikawa, M., Ueno, Y., Fujita, T., Machida, C., Wabiko, H. and Machida, Y. (2006). Oncogene 6b from Agrobacterium tumefaciens induces abaxial cell division at late stages of leaf development and modifies vascular development in petioles. Plant & Cell Physiol. 47, 664-672.
https://doi.org/10.1093/pcp/pcj036

77. Sasabe, M., Soyano, T., Takahashi, Y., Sonobe, S., Igarashi, H., Itoh, TJ., Hidaka, M. and Machida, Y. (2006). Phosphorylation of NtMAP65-1 by a MAP kinase down-regulates its activity of microtubule bundling and stimulates progression of cytokinesis of tobacco cells. Genes & Development 20, 1004-1014.
https://doi.org/10.1101/gad.1408106

76. Gomi, K., Ogawa, D., Katou, S., Kamada, H., Nakajima, N., Saji, H., Soyano, T., Sasabe, M., Machida, Y., Mitsuhara, I., Ohashi, Y. and Seo, S. (2005). A mitogen-activated protein kinase NtMAPK4 activated by SIPKK is required for jasmonic acid signaling and involvement in ozone tolerance via stomatal movement in tobacco. Plant Cell Physiol. 46, 1885-1893.
https://doi.org/10.1093/pcp/pci211

75. Osakabe, K., Abe, K., Yamanouchi, H., Takyuu, T., Yoshioka, T., Itom Y., Kato, T., Tabata, S., Kurei, S., YoshiokaY., Machida, Y., Seki, M., Kobayashi, M., Shinozaki, K., Ichikawa, H. and Toki, S. (2005). Arabidopsis Rad51B is important for double-strand DNA breaks repair in somatic cells. Plant Mol. Biol. 57, 819-833.
https://doi.org/10.1007/s11103-005-2187-1

74. Tanaka, H., Ishikawa, M., Kitamura, S., Takahashi, Y., Soyano, T., Machida, C. and Machida, Y. (2004). The AtNACK1/HINKEL and STUD/TETRASPORE/AtNACK2 genes, which encode functionally redundant kinesins, are essential for cytokinesis in Araidopsis. Genes to Cells 9, 1199-1211.
https://doi.org/10.1111/j.1365-2443.2004.00798.x

73. Asano, T., Yoshioka, Y. and Machida, Y. (2004). A defect in atToc159 of Arabidopsis thalianacauses severe defects in leaf development. Genes & Genetic Systems 79, 207-212.  
https://doi.org/10.1266/ggs.79.207

72. Araki, S., Ito, M., Soyano, T., Nishihama, R. and Machida, Y. (2004). Mitotic cyclins stimulate the activity of c-Myb-like factors for transactivation of G2/M phase-specific genes of tobacco. J. Biol. Chem. 279, 32979 – 32988.
https://doi.org/10.1074/jbc.M403171200

71. Watanabe, M., Tanaka, H., Watanabe, D., Machida, C. and Machida, Y. (2004). The ACR4 receptor-like kinase is required for surface formation of epidermis-related tissues in Arabidopsis thaliana. Plant J. 39, 298-308.
https://doi.org/10.1111/j.1365-313X.2004.02132.x

70. Asano, T., Yoshioka, Y., Kurei, S., Sakamoto, W., Sodmergen. and Machida, Y. (2004). A mutation of the CRUMPLED LEAF gene that encodes a protein localized in the outer envelope membrane of plastids affects the pattern of cell division, cell differentiation, and plastid division in Arabidopsis. Plant J. 38, 448-459.
https://doi.org/10.1111/j.1365-313X.2004.02057.x

69. Moriuchi, H., Okamoto, C., Nishihama, R., Yamashita, I., Machida, Y. and Tanaka, N. (2004). Nuclear localization and interaction of RolB with plant 14-3-3 proteins correlates with induction of adventitious roots by the oncogene rolB. Plant J. 38, 260-275. 
https://doi.org/10.1111/j.1365-313X.2004.02041.x

68. Tanaka, T., Tanaka, H., Machida, C., Watanabe, M. and Machida, Y. (2004). A new method for rapid visualization of defects in leaf cuticle reveals five intrinsic patterns of surface defects in Arabidopsis. Plant J. 37, 139-146.
https://doi.org/10.1046/j.1365-313X.2003.01946.x

67. Soyano, T., Nishihama, R., Morikiyo, K., Ishikawa, M. and Machida, Y. (2003). NQK1/NtMEK1 is a MAPKK that acts in the NPK1 MAPKKK-mediated MAPK cascade and is required for plant cytokinesis. Genes & Development 17, 1055-1067.  
https://doi.org/10.1101/gad.1071103

66. Ishikawa, T., Machida, C., Yoshioka, Y. and Machida, Y. (2003). The GLOBULAR ARREST gene, which is involved in the biosynthesis of folate, is essential for late embryogenesis in Arabidopsis thaliana. Plant J. 33, 235-244.  
https://doi.org/10.1046/j.1365-313x.2003.01621.x

65. Ha, C.-M., Kim, G.-T., Kim, B.-C., Jun, J.-H., Soh, M.-S., Ueno, Y., Machida, Y., Tsukaya, H. and Nam, H.-G. (2003). The BLADE-ON-PETIOLE1 gene controls leaf pattern formation through the modulation of meristematic activity in Arabidopsis. Development 133, 161-172.
https://doi.org/10.1242/dev.00196

64. Ishikawa, M., Soyano, T., Nishihama, R. and Machida, Y. (2002). The NPK1 mitogen-activated protein kinase kinase kinase contains a functional nuclear localization signal at the binding site for the NACK1 kinesin-like protein. Plant J. 32, 789-798.
https://doi.org/10.1046/j.1365-313x.2002.01469.x

63. Soyano, T., Ishikawa, M., Nishihama, R., Araki, S., Ito, M., Ito, M. and Machida, Y. (2002). Control of plant cytokinesis by an NPK1-mediated mitogen-activated protein (MAP) kinase cascade. Philos Trans R Soc Lond B Biol Sci. Jun 29; 357: 767–775. 
https://doi.org/10.1098/rstb.2002.1094

62. Iwakawa, H., Ueno, Y., Semiarti, E., Onouchi, H., Kojima, S., Tsukaya, H., Hasebe, M., Soma, T., Ikezaki, M., Machida, C. and Machida, Y. (2002). The ASYMMETRIC LEAVES2 gene of Arabidopsis thaliana, required for formation of a symmetric flat leaf lamina, encodes a member of a novel family of proteins characterized by cysteine repeats and a leucine zipper. Plant & Cell Physiol. 43, 467-478.
https://doi.org/10.1093/pcp/pcf077

61. Nishihama, R., Soyano, T., Ishikawa, M., Araki, S., Tanaka, H., Asada, T., Irie, K., Ito, M., Terada, M., Banno, H., Yamazaki, Y. and Machida, Y. (2002). Expansion of the Cell Plate in Plant Cytokinesis Requires a Kinesin-Like Protein/MAPKKK Complex. Cell 109, 87-99.
https://doi.org/10.1016/s0092-8674(02)00691-8

60. Tanaka, H., Watanabe, M., Watanabe, D., Tanaka, T., Machida, C. and Machida, Y. (2002). ACR4, a putative receptor kinase gene of Arabidopsis thaliana that is expressed in the outer cell layers of embryos and plants, is involved in proper embryogenesis. Plant & Cell Physiology 43, 419-428.
https://doi.org/10.1093/pcp/pcf052

59. Kitakura, S., Fujita, T., Ueno, Y., Terakura, S., Wabiko, H. and Machida, Y. (2002). The protein encoded by oncogene 6b from Agrobacterium tumefaciens interacts with a nuclear protein of tobacco. The Plant Cell 14, 451-463.
https://doi.org/10.1105/tpc.010360

58. Tanaka, H., Onouchi, H., Kondo, M., Hara-Nishimura, I., Nishimura, M., Machida, C. and Machida, Y. (2001). A subtilisin-like serine protease is required for epidermal surface formation in Arabidopsis embryos and juvenile plants. Development 128, 4681-4689.
https://www.ncbi.nlm.nih.gov/pubmed/11731449

27. Yoshioka, Y., Kurei, S. and Machida, Y. (2001). Identification of a monofunctional aspartate kinase gene of Arabidopsis thaliana with spatially and temporally regulated expression. Genes & Genetic Syst. 76, 189-198.  
https://doi.org/10.1266/ggs.76.189

56. Ito, M., Araki, S., Matsunaga, S., Itoh, T., Nishihama, R., Machida, Y., Doonan, J.- H. and Watanabe, A. (2001). G2/M-phase-specific transcription during the plant cell cycle is mediated by c-Myb-like transcription factors. The Plant Cell 13, 1891-1905.  
https://www.ncbi.nlm.nih.gov/pubmed/11487700

55. Semiarti, E., Onouchi, H., Torikai, S., Ishikawa, T., Machida, Y. and Machida, C. (2001). The transposition pattern of the Ac element in tobacco cultured cells. Genes Genet. Syst. 76, 131-139.
https://doi.org/10.1266/ggs.76.131 

54. Semiarti, E., Ueno, Y., Tsukaya, H., Iwakawa, H., Machida, C. and Machida, Y. (2001). The ASYMMETRIC LEAVES2 gene of Arabidopsis thaliana regulates formation of a symmetric lamina, establishment of venation and repression of meristem-related homeobox genes in leaves. Development 128, 1771-1783.
https://www.ncbi.nlm.nih.gov/pubmed/11311158

53. Nishihama, R., Ishikawa, M., Araki, S., Soyano, T., Asada, T. and Machida, Y. (2001). The NPK1 mitogen-activated kinase kinase kinase is a regulator of cell-plate formation in plant cytokinesis. Genes & Development 15, 352-363.
https://doi.org/10.1101/gad.863701

52. Nakagawa, Y., Machida, C., Machida, Y. and Toriyama, K. (2001). A system to induce deletion of genomic sequences using R/RS site-specific recombination and the Ac transposon in transgenic rice plants. Theor. Appl. Genet. 102, 1136-1141.
https://doi.org/10.1007/s001220100580

51. Hamada, S., Onouchi, H., Tanaka, H., Kudo, M., Liu, Y.-G., Shibata, D., Machida, C. and Machida, Y. (2000). Mutations in the WUSCHEL gene of Arabidopsis thaliana result in the development of shoot without juvenile leaves. Plant J. 24, 91-101.
https://doi.org/10.1046/j.1365-313X.2000.00858.x

50. Toyoda-Yamamoto, A., Shimoda, N. and Machida, Y. (2000). Genetic analysis of the signal sensing region of histidine-protein kinase VirA of Agrobacterium tumefaciens. Mol. Gen. Genet. 263, 939-947.
https://doi.org/10.1007/PL00008694

49. Nakagawa, Y., Machida, C., Machida, Y. and Toriyama, K. (2000). Frequency and pattern of transposition of the maize transposable element Ds in transgenic plants. Plant & Cell Physiology 41, 733-742.
https://doi.org/10.1093/pcp/41.6.733

48. Kojima, S., Banno, H., Yoshioka, Y., Oka, A., Machida, C. and Machida, Y. (1999). A binary vector plasmid for gene expression in plant cells that is stably maintained in agrobacterium cells. DNA Research 6, 407-410.
https://doi.org/10.1093/dnares/6.6.407

47. Bhalerao, R.-P., Salchert, K., Bako, L., Ökresz, L., Szabados, L., Muranaka, T., Machida, Y., Schell, J. and Koncz, C. (1999). Regulatory interaction of PRL1 WD protein with Arabidopsis SNF1-like protein kinases. Proc. Natl. Acad. Sci. USA. vol. 96 no. 9, 5322-5327. 
https://doi.org/10.1073/pnas.96.9.5322

46. Machida, Y., Nakashima, M., Morikiyo, K., Banno, H., Ishikawa, M., Soyano, T. and Nishihama, R. (1998). MAPKKK-related protein kinase NPK1: Regulation of the M phase of plant cell cycle. Journal of Plant Research 111: 243-246. 
https://doi.org/10.1007/BF02512177

45. Nakashima, M., Hirano, K., Nakashima, S., Banno, H., Nishihama, R. and Machida, Y. (1998). The expression pattern of the gene for NPK1 protein kinase related to mitogen-activated protein kinase kinase kinase (MAPKKK) in a tobacco plant: Correlation with cell proliferation. Plant and Cell Physiology, Volume 39, Issue 7, 1 July 1998, Pages 690–700.
https://doi.org/10.1093/oxfordjournals.pcp.a029423

44. Ito M., Iwase M., Kodama H., Lavisse P., Komamine A., Nishihama R., Machida Y. and Watanabe A. (1998). A Novel cis-Acting Element in Promoters of Plant B-Type Cyclin Genes Activates M Phase–Specific Transcription. The Plant Cell Vol. 10, Issue 3, 331–341.
https://doi.org/10.1105/tpc.10.3.331

43. Machida, C., Onouchi, H., Koizumi, J., Hamada, S., Semiarti, E., Torikai, S. and Machida, Y. (1997). Characterization of the transposition pattern of the Ac element in Arabidopsis thaliana using endonuclease I-SceI. Proc. Natl. Acad. Sci. USA 94, 8675-8680.
https://doi.org/10.1073/pnas.94.16.8675

42. Nishihama, R. Banno, H., Kawahara, E., Irie, K. and Machida, Y. (1997). Possible involvement of differential splicing in the regulation of the activity of Arabidopsis ANP1 that is related to mitogen-activated protein kinase kinase kinases (MAPKKKs). Plant J. 12, 39-48.
https://doi.org/10.1046/j.1365-313X.1997.12010039.x

41. Yoshioka, Y., Takahashi, Y., Matsuoka, K., Nakamura, K., Koizumi, J., Kojima, M. and Machida, Y. (1996). Transient Gene Expression in Plant Cells Mediated by Agrobacterium tumefaciens: Application for the Analysis of Virulence Loci. Plant Cell Physiol. 37(6), 782-789.
https://doi.org/10.1093/oxfordjournals.pcp.a029013

40. Usami, S., Banno, H., Ito, Y., Nishihama, R. and Machida, Y. (1995). Cutting activates a 46-kilodalton protein kinase in plants. Proc. Natl. Acad. Sci. USA 92, 8660-8664.
https://doi.org/10.1073/pnas.92.19.8660

39. Onouchi, H., Nishihama, R., Kudo, M., Machida, Y. and Machida, C. (1995). Visualization of site-specific recombination catalized by a recombinase from Zygosaccharomyces rouxii in Arabidopsis thaliana. Mol. Gen. Genet. 247, 653-660. 
https://doi.org/10.1007/BF00290396

38. Shibata, W., Banno, H., Ito, Y., Hirano, K., Irie, K., Usami, S., Machida, C. and Machida, Y. (1995). A tobacco protein kinase, NPK2, has a domain homologous to a domain found in activators of mitogen-activated protein kinases (MAPKKs). Mol. Gen. Genet. 246, 401-410. 
https://doi.org/10.1007/BF00290443

37. Ohba, T., Yoshioka, Y., Machida, C. and Machida, Y. (1995). DNA rearrangement associated with the integration of T-DNA in tobacco: an example for multiple duplications of DNA around the integration target. Plant J. 7, 157-164.
https://doi.org/10.1046/j.1365-313X.1995.07010157.x

36. Niwa, Y., Muranaka, T., Baba, A. and Machida, Y. (1994). Organ-specific and auxin-inducible expression of two tobacco par-related genes in transgenic plants. DNA Research, 1, 213-221.
https://doi.org/10.1093/dnares/1.5.213

35. Ito, Y., Bannno, H., Moribe, T., Hinata, K. and Machida, Y. (1994). NPK15, a tobacco protien-serine/threonine kinase with a single hydrophobic region near the amino terminus. Mol. Gen. Genet. 245, 1-10. 
https://doi.org/10.1007/BF00279745

34. Muranaka, T., Bannno, H. and Machida, Y. (1994). Characterization of Tobacco Protein Kinase NPK5, a Homolog of Saccharomyces cerevisiae SNF1 That Constitutively Activates Expression of the Glucose-Repressible SUC2 Gene for a Secreted Invertase of S. cerevisiae. Mol. Cell Biol. 14, 2958-2965.
https://doi.org/10.1128/MCB.14.5.2958

33. Muranaka, T., Niwa, Y. and Machida, Y. (1994). A model for a bioconversion system with the promoter of the parAt gene, which confers a high level of expression of a transgene in hairy roots. Appl. Microbiol. Biotechnol. 40, 841-845.    
https://doi.org/10.1007/s002530050077

32. Shimoda, N., Toyoda-Yamamoto, A., Aoki, S. and Machida, Y. (1993). Genetic Evidence for an Interaction between the VirA Sensor Protein and the ChvE Sugar-binding protein of Agrobacterium. J. Biol. Chem. 268, 26552-26558.
https://www.ncbi.nlm.nih.gov/pubmed/8253785

31. Bannno, H., Hirano, K., Nakamura, T., Irie, K., Nomoto, S., Matsumoto, K. and Machida, Y. (1993). NPK1, a tobacco gene that encodes a protein with a domain homologous to yeast BCK1, STE11 and Byr2 protein kinases. Mol. Cell Biol. 13, 4745-4752.
https://doi.org/10.1128/MCB.13.8.4745

30. Yoshioka, Y., Matsumoto, S., Kojima, S., Ohshima, K., Okada, N. and Machida, Y. (1993). Molecular characterization of a short interspersed repetitive element (SINE) from tobacco that exhibits sequence homology to specific tRNAs. Proc. Natl. Acad. Sci. USA 90, 6562-6566. 
https://doi.org/10.1073/pnas.90.14.6562

29. Onouchi, H., Yokoi, K., Machida, C., Matsuzaki, H., Ohshima, Y., Matsuoka, K., Nakamura, K. and Machida, Y. (1991). Operation of an efficient site-specific recombination system of Zygosaccharomyces rouxii in tobacco cells. Nucleic Acids Research 19, 6373-6378.
https://doi.org/10.1093/nar/19.23.6373

28. Okamoto, S., Toyoda-Yamamoto, A., Ito, K., Takebe, I. and Machida, Y. (1991). Localization and orientation of the VirD4 protein of Agrobacterium tumefaciens in the cell membrane. Mol. Gen. Genet. 228, 24-32. 
https://doi.org/10.1007/BF00282443

27. Matsumoto, S., Ito, Y., Hosoi, T., Takahashi, Y. and Machida, Y. (1990). Integration of Agrobacterium T-DNA into a tobacco chromosome: possible involvement of DNA homology between T-DNA and plant DNA. Mol. Gen. Genet. 224, 309-316.    
https://doi.org/10.1007/BF00262423

26. Matsuoka, K., Matsumoto, S., Hattori, S., Machida, Y. and Nakamura, K. (1990). Vacuolar targeting and posttraslational processing of the precursor to the sweet potato tuberous root storage protein in heterologous plant cells. J. Biol. Chem. 265, 19750-19757.
https://www.ncbi.nlm.nih.gov/pubmed/2246259

25. Shimoda, N., Toyoda-Yamamoto A., Nagamine, J., Usami, S., Katayama, M., Sakagami, Y. and Machida, Y. (1990). Control of expression of Agrobacterium vir genes by synergistic actions of phenolic signal molecules and monosaccharides. Proc. Natl. Acad. Sci. USA 87, 6684-6688.
https://doi.org/10.1073/pnas.87.17.6684

24. Takahashi, Y., Kuroda, H., Tanaka, T., Machida, Y., Takebe, I. and Nagata, T. (1990). Isolation of an auxin-regulated gene cDNA expressed during the transition from G0 to S phase in tobacco mesophyll protoplasts. Proc. Natl. Acad. Sci. USA 86, 9279-9283. 
https://doi.org/10.1073/pnas.86.23.9279

23. Machida, C. and Machida, Y. (1989). Regulation of IS1 transposition by the insA gene product. J. Mol. Biol. 208, 567-574. 
https://doi.org/10.1016/0022-2836(89)90148-4

22. Niwa, Y., Yamamoto, A., Machida, C, Takebe, I. and Machida Y. (1988). Right-hand border regions of octopine T-DNA are recognized by RNA polymerase of Agrobacterium as well as by VirD1 and virD2 proteins. Nucleic Acids Research 16, 7647-7661.
https://doi.org/10.1093/nar/16.15.7647

21. Okamoto, S., Machida, Y. and Takebe, I. (1988). Subcellular localization of tobacco mosaic virus minus strand RNA in infected protoplast. Virology 167, 194-200.
https://doi.org/10.1016/0042-6822(88)90069-4

20. Usami, S., Okamoto, S., Takebe, I. and Machida, Y. (1988). Novel factor inducing Agrobacteriumtumefaciens vir gene expression is present in monocotyledonous plants. Proc Natl Acad Sci USA. 1988 Jun; 85(11): 3748–3752.
https://doi.org/10.1073/pnas.85.11.3748

19. Matsumoto, S.,Takebe I. and Machida, Y. (1988). Escherichia coli lacZ gene as a biochemical and histochemical marker in plant cells. Gene 66, 19-29.
https://doi.org/10.1016/0378-1119(88)90221-1

18. Machida, C. and Machida, Y. (1987). Base substitutions in transposable element IS1 cause DNA duplication of variable length at the target site for plasmid cointegration. EMBO J. 6, 1799-1803.
https://www.ncbi.nlm.nih.gov/pubmed/3038535

17. Usami, S., Morikawa, S., Takebe, I. and Machida, Y. (1987). Absence in monocotyledonous plants of the plant factors inducing T-DNA circularization and vir gene expression in Agrobacterium. Mol. Gen. Genet. 209, 221-226.
https://doi.org/10.1007/BF00329646

16. Yamamoto, A., Iwahashi, M., Yanofsky, M.- F., Nester, E.- W., Takebe, I. and Machida, Y. (1987). The promoter proximal region in the virD locus of Agrobacterium tumefaciens is necessary for the plant-inducible circularization of T-DNA. Mol. Gen. Genet. 206, 174-177.
https://doi.org/10.1007/BF00326554

15. Machida, Y., Usami, S., Yamamoto, A. and Takebe, I. (1986). Plant-inducible recombination between the 25-base-pair border sequences of T-DNA in Agrobacterium tumefaciens. Mol. Gen. Genet. 204, 374-382.
https://doi.org/10.1007/BF00331013

14. Matsumoto, S., Machida, Y. and Takebe, I. (1986). A rapid method for assaying tumorigenicity of Agrobacterium tumefaciens. Plant Modecular Biology Reporter 4, 42-47.
https://doi.org/10.1007/BF02672488

13. Hashimoto, J. and Machida, Y. (1985). The sequence in potato spindle tuber viroid required for infection of its cDNA: a putative  rocessing site in viroid replication J. Gen. Appl. Microbiol. 31, 551-561.
https://doi.org/10.2323/jgam.31.551

12. Machida, Y., Sakurai, M., Kiyokawa, S., Ubasawa, A., Suzuki, Y. and Ikeda, J.-E (1984). Nucleotide sequence of the IS element found in the T-DNA region of mutant Ti plasmid pTiA66 and distribution of its homologues in octopine Ti plasmid. Proc. Natl. Acad. Sci. USA 81, 7495-7499.
https://doi.org/10.1073/pnas.81.23.7495

11. Machida, C., Machida, Y. and Ohtsubo, E. (1984). Both inverted repeat sequences of the insertion element IS1 provide promorter function for RNA polymerase. J. Mol. Biol. 177, 247-265.
https://doi.org/10.1016/0022-2836(84)90455-8

10. Machida, Y., Machida, C. and Ohtsubo, E. (1984). Insertion element IS1 encodes two structural genes responsible for its transposition. J. Mol. Biol. 177, 229-245.
https://doi.org/10.1016/0022-2836(84)90454-6

9. Armstrong, K.-A., Acosta, R., Lender, E., Machida, Y., Pancotto, M., McCormick, M., Ohtsubo, H. and Ohtsubo, E. (1984). A 37 × 103 molecular weight plasmid-encoded protein is required for replication and copy number control in the plasmid pSC101 and its temperature-sensitive derivative pHS1. J. Mol. Biol. 175, 331-348.
https://doi.org/10.1016/0022-2836(84)90352-8

8. Machida, Y. and Ikeda, J.-E. (1983). Simple method for detection of Ti plasmid DNA in Agrobacterium tumefaciens. Plant Molecular Biology Reporter 1, 39-40.
https://doi.org/10.1007/BF02680261

7. Zenilman, M., Machida, Y., Ohtsubo, H. and Ohtsubo, E. (1983). Inactivation of the replication genes of a pSC101 derivative by IS1-mediated integration of the plasmid pSM1. J. Gen. Appl. Microbiol. 29, 223-232.  
https://doi.org/10.2323/jgam.29.223

6. Machida, C., Machida, Y., Wang, H.-C. R., Ishizaki, K. and Ohtsubo, E. (1983). Repression of cointegration ability of insetion element IS1 by transcriptional readthrough from flanking regions. Cell 34, 135-142.  
https://doi.org/10.1016/0092-8674(83)90143-5

5. Machida, Y., Machida, C. and Ohtsubo, E. (1982). A novel type of transposon generated by insertion element IS102 present in a pSC101 derivative. Cell 30, 29-36.
https://doi.org/10.1016/0092-8674(82)90008-3

4. Machida, Y., Machida, C., Ohtsubo, H. and Ohtsubo, E. (1982). Factors determining frequency of plasmid cointegration mediated by insertion sequence IS1. Proc. Natl. Acad. Sci. USA 79, 277-281.
https://www.ncbi.nlm.nih.gov/pubmed/345709

3. Machida, Y., Okazaki, T., Miyake, T., Ohtsuka, E. and Ikehara, M. (1981). Characterization of Nascent DNA Fragments Produced by Excision of Uracil Residues in DNA. Nucleic Acids Research 9, 4755-4766.  
https://doi.org/10.1093/nar/9.18.4755

2. Wada, A., Tachibana, H., Ueno, S., Hushimi, Y. and Machida, Y. (1977). Melting Fine Structure of DNA Fragments of Known Sequence from φX174. Nature 269, 352-353.
https://doi.org/10.1038/269352a0

1. Machida, Y., Okazaki, T. and Okazaki, R. (1977). Discontinuous Replication of Replicative Form DNA from Bacteriophage φX174. Proc. Natl. Acad. Sci. USA. 74, 2776-2779.  
https://doi.org/10.1073/pnas.74.7.2776



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